by abs-adm | Apr 23, 2020 | blog post
PROTAC (PROteolysis TArgeting Chimera) is one of the hottest topics in drug discovery today as it is a highly promising new approach to targeted therapy. It offers several advantages over traditional occupancy-based drugs, with a potential to target the ‘undruggable’... by abs-adm | Jul 8, 2019 | blog post
New, innovative solutions in cell biology are constantly being developed to support biological research, and can be applied to the drug discovery process. However, in order to convince the scientific community of the promises these applications offer, they need to be... by abs-adm | Apr 26, 2019 | blog post
Kinases are one of the most significant classes of drug targets because of their involvement in several diseases including cancer, osteoporosis, inflammatory disease, diabetes and neurodegeneration. Identification of candidate drugs targeting kinases relies on... by abs-adm | Mar 20, 2019 | blog post
The role of kinases in human disease is well known in the drug discovery world, making them significant therapeutic intervention points. There are over 500 known kinases in the human kinome and over 150 are mutated or mis regulated in various disease states. However,... by abs-adm | Dec 13, 2018 | blog post
GPCRs (G-protein-coupled receptors) are the largest and most diverse family of membrane proteins that transduce extracellular stimuli into intracellular signals. Their association with several human diseases has made them a hot topic of research in the pharmaceutical... by abs-adm | Aug 23, 2018 | blog post
Decades of research has resulted in better understanding of the physiological function and molecular properties of proteins. As proteins rarely act alone, a critical step towards unravelling the complex molecular relationships has been examination of protein- protein...