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Specialised Technologies

Label-Free Screening

Label-Free Screening

Our scientists have in-depth experience of label-free technology applied to cell-based assays gained over the past 6 years using Coring EPIC, Perkin Elmer EnSpire and SRU Bioscience Bind instruments.

 FLIPR Screening

FLIPR Screening

We have used FLIPR in a range of assay formats, readouts and target types.

FMAT Screening

FMAT Screening

The 8200 Cellular Detection System (Fluorescent Microvolume Assay Technology – FMAT) from Applied Biosystems is a laser scanning macro-confocal fluorescent plate reader.

High Content Screening

High Content Screening

We have used the CellInsight CX5 and Image Express Ultra imaging devices in a range of assay formats involving different target types.

WES

Wes: Western Assay System

We have recently added a Wes system from ProteinSimple to our technology bank. The Wes is a fully automated, highly reproducible and sensitive alternative to standard Western blotting assays.

Hypoxia

Hypoxia and Cancer

We have developed a physiologically relevant human cell-based assay to screen small molecules for their ability to inhibit such adaptive responses to hypoxia.

Hypoxia

Quantitative PCR

Using our Applied Biosystems™ QuantStudio™ 6 Flex Real-Time PCR system, we are able to investigate quantitative differences in mRNA expression in relation to pathways and targets identified as being of interest to clients.