Our scientists have in-depth experience of label-free technology applied to cell-based assays gained over the past 6 years using Coring EPIC, Perkin Elmer EnSpire and SRU Bioscience Bind instruments.
The 8200 Cellular Detection System (Fluorescent Microvolume Assay Technology – FMAT) from Applied Biosystems is a laser scanning macro-confocal fluorescent plate reader.
We have used the CellInsight CX5 and Image Express Ultra imaging devices in a range of assay formats involving different target types.
We have recently added a Wes system from ProteinSimple to our technology bank. The Wes is a fully automated, highly reproducible and sensitive alternative to standard Western blotting assays.
We have developed a physiologically relevant human cell-based assay to screen small molecules for their ability to inhibit such adaptive responses to hypoxia.
Using our Applied Biosystems™ QuantStudio™ 6 Flex Real-Time PCR system, we are able to investigate quantitative differences in mRNA expression in relation to pathways and targets identified as being of interest to clients.
We have developed a novel 3D cell culture system for cell based compound screening and phenotypic drug discovery in a high throughput multiwell plate setting.The new technology offers unique the ability to accommodate any cell type in any assay at any throughput required.