Kathy Dodgson presented a poster at #ELRIGDD17 on work carried out by Aurelia Bioscience to develop bioassays for autophagy (the natural, regulated, destructive mechanism of the cell that disassembles unnecessary or dysfunctional components). Evidence indicates that the predominant role of autophagy in cancer cells is to confer stress tolerance that can maintain tumor cell survival. Knockdown of essential genes in tumor cells has been shown to confer or potentiate the induction of cell death. If you click on the link above, it will take you to our poster which describes the development of an autophagy assay in some detail.

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