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In recent years, there have been significant advances in technologies and their application to biology that have impacted drug discovery. Excitingly, this rapid rate of innovation shows no sign of slowing down, offering drug discovery researchers vast possibilities when it comes to bioassay development.
Here we highlight some of the upcoming trends in drug screening technologies that could greatly enhance the impact of your research, helping you to build even more sophisticated bioassays and keep you at the forefront of drug discovery.
Bioassays are an essential tool for early drug discovery. By helping to identify ‘hit’ compounds that effectively act on a biological target involved in a disease pathway, bioassays underpin key decisions about compound progression. Without a well optimised bioassay, fewer ‘hits’ would be translated into new drugs that could improve patients’ lives.
In previous blogs, we have offered a range of practical advice on bioassay design and development to facilitate reliable data-driven decisions during early drug discovery. Following these key principles and guidelines is a crucial step towards developing successful bioassays, but even then, you are still likely to encounter some obstacles. Below we take a look at some of the most common challenges you might face and offer advice on how to overcome them.
Bioassays are an essential tool for early drug discovery. They allow researchers to identify the few promising compounds that have the potential to become precursors of new medicines. In previous blogs, we’ve explored the key principles of bioassay design and practicalities of bioassay construction. Here we look at how you can carry out bioassay validation to confirm that your bioassay is fit-for-purpose.
Read on to find out more about the key guidelines and statistical rules you should follow to ensure your bioassays are reproducible and consistent. These will help you make data-driven decisions about the compounds that could make or break the success of your drug discovery research